Description

Phenylthiohydantoin Leucine is a specialized derivative of the amino acid leucine, primarily used as a key intermediate in peptide synthesis and analytical chemistry. This compound is critical for researchers and manufacturers requiring high-purity building blocks for advanced biochemical applications. It is essential for industries focused on pharmaceutical development, proteomics research, and the synthesis of complex organic molecules.

Application

• Peptide Synthesis Intermediate: A crucial building block in solid-phase and solution-phase peptide synthesis.
• Edman Degradation Reagent: Used in protein sequencing to identify amino acid residues.
• Pharmaceutical Research: Serves as an intermediate in the development of novel active pharmaceutical ingredients (APIs).
• Biochemical Analysis: Employed in analytical standards and reference materials for chromatographic methods like HPLC.
• Proteomics & Genomics: Utilized in advanced research for studying protein structure and function.
• Organic Synthesis: Acts as a precursor for synthesizing more complex heterocyclic compounds and fine chemicals.

Basic Information

Item	Detail
Product Name	Phenylthiohydantoin Leucine
CAS No.	29588-99-6
Molecular Formula	C13H16N2O2S
Molecular Weight	264.34 g/mol
Synonyms	PTH-Leucine; 3-Phenyl-2-thiohydantoin leucine; Leucine phenylthiohydantoin; 2-Thio-5-oxo-4-(2-methylpropyl)imidazolidine-4-carboxylic acid phenyl derivative; (4S)-4-(2-Methylpropyl)-2-sulfanylidene-5-oxo-1,3-diazolidine-4-carboxylic acid phenyl derivative; Edman degradation product of leucine; Leucine PTH derivative
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Leucine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.