Description

Tabersonine Hydrochloride is a high-purity alkaloid salt derived from the *Catharanthus roseus* plant, valued for its role as a critical intermediate in pharmaceutical research and synthesis. Its primary significance lies in its structural relationship to vinblastine and vincristine, making it a key building block for developing novel anticancer agents and other bioactive compounds. This product is essential for research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on oncology drug discovery and natural product chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the semi-synthesis of complex bisindole alkaloids with therapeutic potential.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships and mechanisms of action related to microtubule inhibition.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for quality control and method validation of related alkaloid products.
• Academic & Discovery Chemistry: A valuable starting material for medicinal chemists exploring new derivatives and analogs for drug discovery programs.
• Biochemical Reagent: Utilized in enzymatic studies and as a tool compound for probing biological pathways in cell-based assays.

Basic Information

Product Name	Tabersonine Hydrochloride
CAS No.	29479-00-3
Molecular Formula	C21H25ClN2O2
Molecular Weight	372.89 g/mol
Synonyms	Tabersonine HCl; 16-Epivincamine hydrochloride; (19S)-19-Ethyl-19-hydroxy-1-methyl-6,7-didehydroaspidospermidin-3-one hydrochloride; Catharanthine analog hydrochloride; 3-Oxotabersonine hydrochloride; 16-Epi-vincamine hydrochloride; Lochneram hydrochloride (related); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Tabersonine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.