Description

Tetrahydroberberine is a key hydrogenated derivative of the natural alkaloid berberine, offering distinct chemical and biological properties. This compound is valued for its enhanced stability and bioavailability compared to its parent molecule, making it a crucial intermediate for advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and life science research sectors for applications in metabolic and neurological studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents targeting metabolic pathways.
• Nutraceutical Research: Investigated as a potential active ingredient in dietary supplements focused on metabolic health and wellness.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to understand enzyme interactions and cellular signaling.
• Academic & Institutional Research: Employed in universities and research institutes for studying the structure-activity relationships of isoquinoline alkaloids.
• Preclinical Development: Utilized in animal model studies to evaluate efficacy, pharmacokinetics, and safety profiles.

Basic Information

Product Name	Tetrahydroberberine
CAS No.	29074-38-2
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Canadine; 5,6,13,13a-Tetrahydro-9,10-dimethoxy-6-methyl-8H-dibenzo[a,g]quinolizine-2,3-diol; 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6-methyl-8H-dibenzo[a,g]quinolizine-2,3-diol; Tetrahydroberberine; (13aS)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6-methyl-8H-dibenzo[a,g]quinolizine-2,3-diol; NSC 172906; THB
EINECS	Contact for details

Quality Control

Our Tetrahydroberberine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets rigorous standards for research and development purposes. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.