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4-Fluoro-1-Nitro-2-Propoxybenzene CAS NO 28987-45-3


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CAS No.:28987-45-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluoro-1-Nitro-2-Propoxybenzene is a specialized aromatic nitro compound featuring a propoxy and a fluorine substituent, making it a valuable fluorinated intermediate in advanced organic synthesis. Its molecular structure is engineered to facilitate selective chemical transformations, particularly in the construction of complex pharmacophores and agrochemicals. This high-purity intermediate is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated aromatic systems into their target molecules.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic rings to modulate bioavailability and metabolic stability.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental persistence.
  • Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
  • Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, color-fast dyes and organic pigments.
  • Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
  • Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Item Details
Product Name 4-Fluoro-1-Nitro-2-Propoxybenzene
CAS No. 28987-45-3
Molecular Formula C9H10FNO3
Molecular Weight 199.18 g/mol
Synonyms 1-Fluoro-4-nitro-2-propoxybenzene; 2-Propoxy-4-fluoro-1-nitrobenzene; 4-Fluoro-2-propoxy-1-nitrobenzene; 4-Fluoro-1-nitro-2-propoxy-benzene; 4-Fluoro-2-propoxy-nitrobenzene; 2-Propoxy-4-fluoronitrobenzene; 1-Nitro-4-fluoro-2-propoxybenzene
EINECS Contact for details

Quality Control

Every batch of 4-Fluoro-1-Nitro-2-Propoxybenzene is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, NMR, and FTIR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance Yellow to light brown crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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