Description

L-Dicentrine is a high-purity, naturally derived isoquinoline alkaloid with significant pharmacological research interest. Its unique stereochemistry and biological activity make it a valuable reference standard and a key intermediate in the development of novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on neuroscience, cardiovascular, and anti-inflammatory applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug discovery and manufacturing.
• Biochemical Research: Serves as a key intermediate or active compound in studies targeting adrenergic receptors, calcium channels, and other neurological pathways.
• Natural Product Synthesis: Acts as a chiral building block or precursor in the semi-synthesis of complex natural products and novel drug candidates.
• Academic & Contract Research: Utilized in university and CRO laboratories for pharmacological screening, mechanism of action studies, and toxicity assessments.
• Fine Chemical Intermediate: Employed in the production of specialized, high-value chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	L-Dicentrine
CAS No.	28832-07-7
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	(-)-Dicentrine; (S)-Dicentrine; Dicentrine, L-; L(-)-Dicentrine; 1,2,9,10-Tetramethoxy-6a,7-dihydro-4H-dibenzo[de,g]quinoline; 5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-7-methyl-4H-dibenzo[de,g]quinoline; (6aS)-1,2,9,10-Tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
EINECS	Contact for details

Quality Control

Our L-Dicentrine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is accompanied by a detailed Certificate of Analysis (COA). We support research and development with materials suitable for use as analytical standards, adhering to relevant guidelines for identity, strength, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.