Description

Estriol Glucuronide is a crucial conjugated metabolite of the endogenous estrogen, estriol. This compound is of significant importance as a high-purity reference standard and an analytical reagent in clinical and pharmaceutical research. It is primarily needed by manufacturers and research institutions in the pharmaceutical, diagnostic, and life science sectors for applications such as method development, quality control, and biomarker studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative analysis of estriol metabolites in drug development and quality control laboratories.
• Clinical Diagnostics: Serves as a critical calibrator and control in the development and validation of immunoassays and LC-MS/MS methods for hormone level testing.
• Biomedical Research: Employed in studies investigating estrogen metabolism, pharmacokinetics, and the role of hormone conjugates in various physiological and pathological states.
• Doping Control: Utilized as a reference compound in anti-doping laboratories for the precise detection and confirmation of endogenous steroid metabolites in athletes.
• Metabolite Identification: Acts as a definitive standard in mass spectrometry-based studies for the identification and characterization of estrogen-related metabolites.

Basic Information

Product Name	Estriol Glucuronide
CAS No.	28808-07-3
Molecular Formula	C24H32O9
Molecular Weight	464.51 g/mol
Synonyms	Estriol 16α-Glucuronide; Estriol 16-Glucuronide; 16α-Hydroxyestriol 16-Glucuronide; Estr-5(10)-ene-3,16α,17β-triol 16-glucuronide; 16α-Hydroxy-17β-estradiol 16-glucuronide; 1,3,5(10)-Estratrien-3,16α,17β-triol 16-(β-D-glucopyranosiduronic acid)
EINECS	Contact for details

Quality Control

Our Estriol Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.