Description

4-Methylumbelliferyl2,3,4,6-Tetra-o-Acetyl-A-D-Mannopyranoside is a specialized fluorogenic glycosidase substrate used extensively in biochemical research and diagnostic applications. This compound is critical for the sensitive detection and quantification of α-mannosidase enzyme activity. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic kit manufacturers engaged in enzyme kinetics studies, high-throughput screening, and the development of assays for lysosomal storage disorders.

Application

• Enzyme Activity Assays: A key fluorogenic substrate for the detection and kinetic analysis of α-D-mannosidase and related glycosidase enzymes.
• Diagnostic Development: Used in the formulation of diagnostic kits for genetic disorders such as α-mannosidosis.
• Biochemical Research: Essential for studying glycosidase inhibition, enzyme mechanisms, and carbohydrate metabolism in vitro.
• High-Throughput Screening (HTS): Employed in pharmaceutical research to screen for potential glycosidase inhibitors as drug candidates.
• Lysosomal Function Studies: A tool for investigating lysosomal enzyme activity and function in cell biology.
• Quality Control in Biologics: Can be used to monitor enzyme activity during the production and purification of therapeutic proteins.

Basic Information

Product Name	4-Methylumbelliferyl2,3,4,6-Tetra-o-Acetyl-A-D-Mannopyranoside
CAS No.	28541-71-1
Molecular Formula	C26H30O14
Molecular Weight	566.51 g/mol
Synonyms	4-MU-α-D-Manp-(Ac)4; 4-Methylumbelliferyl α-D-mannopyranoside tetraacetate; 4-Methylumbelliferyl-2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside; α-4-Methylumbelliferyl mannopyranoside tetraacetate; 4-MU-α-Man(Ac)4; Fluorogenic α-mannosidase substrate; 4-Methylumbelliferyl α-mannoside tetraacetate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl2,3,4,6-Tetra-o-Acetyl-A-D-Mannopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our global customer base in pharmaceutical development and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.