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D-Myo-Inositol, 1-(2R)-2,3-Bis(1-Oxohexadecyl)Oxypropyl Hydrogen Phosphate CAS NO 28366-80-5


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CAS No.:28366-80-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Myo-Inositol, 1-(2R)-2,3-Bis(1-Oxohexadecyl)Oxypropyl Hydrogen Phosphate is a complex phospholipid derivative of inositol, specifically a phosphatidylinositol (PI) analog with defined stereochemistry and palmitoyl side chains. This compound is of significant value as a high-purity biochemical standard and a critical intermediate in lipidomics research and the synthesis of more complex signaling molecules. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on lipid biochemistry, cell signaling pathways, and metabolic studies.

Application

  • Biochemical Research Standard: Used as a certified reference material for the analysis and quantification of phosphatidylinositols and related lipids in mass spectrometry and chromatography.
  • Cell Signaling Studies: Serves as a precursor or analog in research investigating the phosphoinositide (PI) cycle, intracellular signaling, and membrane dynamics.
  • Pharmaceutical Intermediate: Acts as a key building block in the synthesis of novel therapeutic agents targeting lipid-mediated pathways.
  • Lipidomics: Essential for creating calibration curves and method development in lipidomic profiling to understand lipid metabolism and disease states.
  • Enzyme Substrate/Inhibitor: Potential use as a substrate for kinases, phosphatases, or phospholipases in enzymatic activity assays and inhibitor screening.
  • Membrane Biophysics: Used in model membrane systems (e.g., liposomes, bilayers) to study the biophysical properties and functions of specific phospholipids.

Basic Information

Product Name D-Myo-Inositol, 1-(2R)-2,3-Bis(1-Oxohexadecyl)Oxypropyl Hydrogen Phosphate
CAS No. 28366-80-5
Molecular Formula C41H79O12P
Molecular Weight 795.03 g/mol
Synonyms 1-Palmitoyl-2-palmitoyl-sn-glycero-3-phospho-(1D-myo-inositol); PI(16:0/16:0); Phosphatidylinositol (16:0/16:0); 1,2-Dipalmitoyl-phosphatidylinositol; Dipalmitoyl Phosphatidylinositol; PtdIns(16:0/16:0); 1,2-Dihexadecanoyl-sn-glycero-3-phospho-(1-myo-inositol); (2R)-2,3-Bis(palmitoyloxy)propyl (1R,2S,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl phosphate
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and lipid composition. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a strict quality management system to ensure traceability and consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated at low temperature.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (TLC) Single spot
Water Content (KF) ≤ 1.0%
Solvent Residue (GC) Meets ICH guidelines
Fatty Acid Composition (GC) ≥ 98% C16:0 (Palmitic acid)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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