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D-Palmitoylcarnitine Chloride CAS NO 28330-02-1
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CAS No.:28330-02-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-Palmitoylcarnitine Chloride is a high-purity, enantiomerically pure form of palmitoylcarnitine, a critical intermediate in fatty acid metabolism. This compound is essential for research and development in metabolic studies, serving as a key reference standard and biochemical tool. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic reagents focused on cardiometabolic and mitochondrial disorders.
Application
- Biochemical Research: Used as a reference standard and substrate in studies of carnitine palmitoyltransferase (CPT) I and II enzyme activity, fatty acid β-oxidation, and mitochondrial function.
- Pharmaceutical Development: Serves as a critical intermediate and analytical standard in the development of therapeutics targeting metabolic syndromes, cardiac ischemia, and disorders of fatty acid metabolism.
- Diagnostic Manufacturing: Employed in the production of calibrators, controls, and assay kits for clinical diagnostics related to metabolic and genetic disorders (e.g., CPT deficiency).
- Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate lipid-induced insulin resistance, apoptosis, and the role of acylcarnitines in cellular signaling pathways.
- Metabolomics & Biomarker Discovery: Acts as a certified reference material for the accurate quantification of acylcarnitine profiles in mass spectrometry-based metabolomic studies.
- Nutritional Science Research: Utilized in studies examining the role of carnitine and its esters in energy metabolism, exercise physiology, and nutritional supplements.
Basic Information
| Product Name | D-Palmitoylcarnitine Chloride |
| CAS No. | 28330-02-1 |
| Molecular Formula | C23H46ClNO4 |
| Molecular Weight | 436.07 g/mol |
| Synonyms | D-Palmitoyl-L-carnitine chloride; (R)-Palmitoylcarnitine chloride; (3R)-3-(Hexadecanoyloxy)-4-(trimethylammonio)butanoate Chloride; D-O-Palmitoylcarnitine chloride; D-(-)-Palmitoylcarnitine chloride; Palmitoyl-D-carnitine chloride; (R)-3-Palmitoyloxy-4-(trimethylammonio)butyrate chloride |
| EINECS | Contact for details |
Quality Control
Our D-Palmitoylcarnitine Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and diagnostic applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystals |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% (D-isomer) |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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