Description

4-Methylphenyl 1-Thio-B-D-Galactopyranoside is a specialized thioglycoside derivative used as a critical biochemical reagent. This compound serves as a chromogenic substrate for the detection and study of β-galactosidase activity in molecular biology and diagnostic applications. It is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and in vitro diagnostic (IVD) kit production who require high-purity, reliable enzyme substrates.

Application

• Enzyme Substrate for β-Galactosidase: Used as a chromogenic substrate in assays to detect and quantify β-galactosidase activity, a common reporter gene in molecular biology.
• Molecular Biology Research: Essential for gene expression studies, promoter analysis, and bacterial colony screening (e.g., blue-white screening in cloning).
• Diagnostic Reagent Manufacturing: A key raw material in the formulation of diagnostic kits for clinical and research laboratories.
• Biochemical Research: Employed in enzymatic studies to investigate enzyme kinetics, inhibition, and mechanism of action.
• Cell-based Assays: Used in high-throughput screening (HTS) and cell biology to monitor cellular processes linked to reporter gene expression.
• Pharmaceutical Development: Utilized in drug discovery pipelines for screening compounds that modulate gene expression or enzyme function.

Basic Information

Product Name	4-Methylphenyl 1-Thio-B-D-Galactopyranoside
CAS No.	28244-98-6
Molecular Formula	C₁₃H₁₈O₅S
Molecular Weight	286.34 g/mol
Synonyms	p-Methylphenyl 1-Thio-β-D-galactopyranoside; 4-Methylphenyl β-D-thiogalactopyranoside; p-Methylphenyl β-D-thiogalactoside; 1-Thio-4-methylphenyl β-D-galactopyranoside; PTG (p-Methylphenyl thiogalactoside); Thiogalactoside derivative; Galactopyranoside thioglycoside; 4-Methylphenyl thiogalactoside
EINECS	Contact for details

Quality Control

Our 4-Methylphenyl 1-Thio-B-D-Galactopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.