Description

α-Dansyl-L-Arginine Hydrochloride is a high-purity, fluorescently labeled derivative of the amino acid L-arginine, widely used as a critical substrate and reference standard in biochemical research and diagnostic applications. Its core value lies in its dansyl fluorophore, which enables sensitive detection and quantification in enzymatic assays and analytical methods. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, clinical diagnostics, and proteomics who require precise, reliable reagents for studying enzyme kinetics and protein interactions.

Application

• Enzymology Research: Primary substrate for the assay of trypsin, thrombin, and other serine proteases, facilitating kinetic studies and inhibitor screening.
• Diagnostic Kit Manufacturing: Key component in the formulation of diagnostic kits for measuring pancreatic function and coagulation disorders.
• Pharmaceutical Development: Used as a reference standard in quality control and method development for peptide-based drug candidates.
• Proteomics & Biochemical Analysis: Employed in fluorescence-based assays for protein digestion monitoring and protease activity profiling.
• Academic & Industrial R&D: Serves as a vital tool in life science research for investigating enzymatic pathways and mechanisms.

Basic Information

Product Name	α-Dansyl-L-Arginine Hydrochloride
CAS No.	28217-22-3
Molecular Formula	C20H31ClN6O4S
Molecular Weight	487.02 g/mol
Synonyms	Nα-Dansyl-L-arginine hydrochloride; 5-(Dimethylamino)naphthalene-1-sulfonyl-L-arginine hydrochloride; DNS-Arg-OH·HCl; L-Arginine, N2-[5-(dimethylamino)-1-naphthalenesulfonyl]-, hydrochloride (1:1); Dansylarginine hydrochloride; N-Dansyl-L-arginine HCl; Nα-DNS-L-Arg·HCl
EINECS	Contact for details

Quality Control

Our α-Dansyl-L-Arginine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and in-vitro diagnostic use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant industry guidelines, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.