Description

(3Alpha,14Beta,16Alpha)-14,15-Dihydro-14-Hydroxyeburnamenine-14-Carboxylic Acid is a high-purity, complex indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) for process development and quality control.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for developing new alkaloid-based drugs.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing to ensure product identity and purity.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and mechanism of action for eburnane alkaloids.
• Process Chemistry: Serves as a starting material or intermediate in scaling up the production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(3Alpha,14Beta,16Alpha)-14,15-Dihydro-14-Hydroxyeburnamenine-14-Carboxylic Acid
CAS No.	28152-73-0
Molecular Formula	C19H24N2O3
Molecular Weight	328.41 g/mol
Synonyms	14-Hydroxyeburnamenine-14-carboxylic acid; Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-; (-)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid; Vincamine derivative; Eburnane alkaloid intermediate; Apovincaminic acid derivative; (3α,14β,16α)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid
EINECS	Contact for details

Quality Control

Our (3Alpha,14Beta,16Alpha)-14,15-Dihydro-14-Hydroxyeburnamenine-14-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.