Description

5-Thyminyl-5,6-Dihydrothymine is a specialized heterocyclic organic compound, a dimeric derivative of thymine. This compound is of significant interest in biochemical and pharmaceutical research due to its structural relationship to DNA components. It serves as a critical intermediate and reference standard for scientists developing novel therapeutic agents and studying nucleic acid chemistry and radiation biology.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel nucleoside analogs and potential antiviral or anticancer agents.
• Biochemical Studies: Used as a reference standard and probe in research focused on DNA damage, repair mechanisms, and the effects of ionizing radiation.
• Academic Research: Essential compound for universities and research institutions studying organic synthesis, heterocyclic chemistry, and photochemistry.
• Analytical Standard: Serves as a high-purity calibration standard for analytical methods (HPLC, LC-MS) in quality control laboratories.
• Radioprotectant Studies: Investigated for its potential role in understanding and mitigating radiation-induced cellular damage.

Basic Information

Product Name	5-Thyminyl-5,6-Dihydrothymine
CAS No.	28100-77-8
Molecular Formula	C10H14N4O4
Molecular Weight	254.24 g/mol
Synonyms	Thymine Dimer; cis-syn Thymine Dimer; 5,6-Dihydro-5-(thymin-1-yl)thymine; 1,3-Dimethyl-5,6-dihydro-5-(1,2,3,4-tetrahydro-2,4-dioxo-5-methylpyrimidin-1-yl)pyrimidine-2,4(1H,3H)-dione; Cyclobutadithymine; TT Dimer; Dihydrothymine Dimer
EINECS	Contact for details

Quality Control

Our 5-Thyminyl-5,6-Dihydrothymine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.