Description

Pregnane-3,20-Diol 3,20-Disulfate is a high-purity, disulfated steroid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for the synthesis and analysis of complex steroid hormones and their metabolites. It is primarily utilized by research institutions and pharmaceutical companies engaged in endocrinology, metabolic pathway studies, and the development of novel therapeutic agents. The product, identified by CAS No. 27935-53-1, is supplied with full analytical documentation to ensure traceability and reliability for sensitive applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of assay methods in quality control laboratories.
• Biochemical Research: A key intermediate in the study of steroid metabolism, sulfation pathways, and enzyme activity related to hormone biosynthesis and regulation.
• Drug Discovery & Development: Serves as a building block or a metabolite analog in the synthesis and screening of new drug candidates targeting hormonal receptors.
• Diagnostic Kit Manufacturing: Employed in the production of immunoassays and diagnostic kits for the quantitative detection of specific steroid metabolites in clinical samples.
• Academic Research: Utilized in university and institutional labs for fundamental research into endocrinology, reproductive biology, and metabolic disorders.

Basic Information

Product Name	Pregnane-3,20-Diol 3,20-Disulfate
CAS No.	27935-53-1
Molecular Formula	C21H34O8S2
Molecular Weight	478.61 g/mol
Synonyms	Pregnane-3α,20α-diol 3,20-Disulfate; 3α,20α-Dihydroxy-5β-pregnane 3,20-Disulfate; 5β-Pregnane-3α,20α-diol 3,20-Disulfate; 3α,20α-Dihydroxy-5β-pregnane Disulfate; Pregnane Diol Disulfate; Pregn-3,20-Diol Disulfate; 5β-Pregnanediol Disulfate
EINECS	Contact for details

Quality Control

Every batch of Pregnane-3,20-Diol 3,20-Disulfate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.