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1,2-Diundecanoyl-Sn-Glycero-3-Phosphocholine CAS NO 27869-47-2


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CAS No.:27869-47-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Diundecanoyl-Sn-Glycero-3-Phosphocholine is a synthetic, medium-chain phospholipid that serves as a critical building block for advanced lipid-based formulations. Its defined structure and high purity make it an essential material for researchers and manufacturers requiring precise and reproducible lipid behavior. This compound is primarily utilized in the development of liposomes, lipid nanoparticles (LNPs), and other model membrane systems for drug delivery, diagnostics, and fundamental biophysical research.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for creating stable, uniform vesicles for encapsulating active pharmaceutical ingredients (APIs), including mRNA, siRNA, and small molecule drugs.
  • Model Membrane Studies: Used to construct defined lipid bilayers for investigating membrane protein interactions, permeability, and fusion mechanisms in biophysical research.
  • Drug Delivery System Development: Serves as a structural lipid to enhance the stability, targeting, and controlled release profiles of nano-carrier systems.
  • Diagnostic Reagents: Incorporated into lipid-based assays and sensors where consistent surface properties and compatibility with biological systems are required.
  • Biomimetic Coatings: Applied in surface modification to create biocompatible interfaces for medical devices and implants.
  • Excipient for Advanced Formulations: Used as a functional excipient in preclinical and clinical-stage formulations requiring specific lipid compositions.

Basic Information

Product Name 1,2-Diundecanoyl-Sn-Glycero-3-Phosphocholine
CAS No. 27869-47-2
Molecular Formula C30H60NO8P
Molecular Weight 593.78 g/mol
Synonyms 1,2-Diundecanoylphosphatidylcholine; PC(22:0/22:0); Dielaidoylphosphatidylcholine (C11:0); 1,2-Diundecanoyl-rac-glycero-3-phosphocholine; DLPC (C11:0); Phosphatidylcholine, 1,2-diundecanoyl-; 3-sn-Phosphatidylcholine, 1,2-diundecanoyl-; L-α-Phosphatidylcholine, diundecanoyl-
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Quality Control

Our 1,2-Diundecanoyl-Sn-Glycero-3-Phosphocholine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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