Description

N(4)-Methyl-5-Azacytidine is a chemically modified nucleoside analog of cytidine, designed for enhanced stability and specific biological activity. This compound is of significant interest in pharmaceutical research and development, particularly in the field of epigenetics and oncology. It serves as a valuable building block and reference standard for researchers and manufacturers in the life sciences sector, enabling the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel nucleoside-based therapeutics.
• Epigenetic Research: Used as a research tool in studies involving DNA methylation and gene expression regulation.
• Oncology Drug Discovery: Investigated for its potential role in the synthesis of chemotherapeutic agents targeting cancer cell proliferation.
• Biochemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.
• Academic & Institutional Research: Employed in university and research institute settings for fundamental studies in medicinal chemistry and molecular biology.

Basic Information

Product Name	N(4)-Methyl-5-Azacytidine
CAS No.	27826-76-2
Molecular Formula	C9H13N5O5
Molecular Weight	271.23 g/mol
Synonyms	4-Methyl-5-azacytidine; 4-Methyl-5-aza-2'-deoxycytidine; 1-(2-Deoxy-β-D-ribofuranosyl)-4-methyl-1,3,5-triazin-2(1H)-one; 4-Methyl-5-aza-2'-deoxycytidine; 4-Methyl-5-aza-dC; 4-Me-5-aza-CdR; 4-Methyl-5-aza-2'-deoxycytidine (N(4)-Methyl-5-Azacytidine)
EINECS	Contact for details

Quality Control

Our N(4)-Methyl-5-Azacytidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.