Description

[(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxyphosphonic Acid is a high-purity, phosphorylated sugar derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial synthetic intermediate and biochemical probe for studying enzyme mechanisms and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers focused on glycoscience, drug discovery, and the synthesis of novel bioactive molecules.

Application

• Biochemical Research: Acts as a substrate or inhibitor for studying glycosyltransferases, phosphatases, and other carbohydrate-processing enzymes.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of nucleotide analogs, glycomimetics, and potential therapeutic agents targeting metabolic disorders.
• Metabolic Pathway Analysis: Used as a tracer or probe compound to investigate sugar phosphate metabolism and related cellular processes.
• Enzyme Mechanism Studies: Provides insights into phosphorylation/dephosphorylation kinetics and transition state analogs for enzyme characterization.
• Glycoconjugate Synthesis: A precursor for creating phosphorylated glycans and complex carbohydrate structures for immunological and diagnostic applications.
• Academic & Industrial R&D: Fundamental research tool in chemistry and biology departments, as well as in biotech companies developing enzyme-based technologies.

Basic Information

Product Name	[(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxyphosphonic Acid
CAS No.	27251-84-9
Molecular Formula	C6H13O9P
Molecular Weight	260.14 g/mol
Synonyms	D-Glucose 1-Phosphate; α-D-Glucopyranose 1-Phosphate; Cori Ester; Glucose-1-phosphoric Acid; D-Glucose-1-phosphate; α-D-Glucose 1-phosphate; 1-O-Phosphono-α-D-glucopyranose; α-D-Glucopyranosyl phosphate
EINECS	Contact for details

Quality Control

Our [(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxyphosphonic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.