Description

Bilirubin Glucuronate is a crucial conjugated form of bilirubin, a key metabolite in the heme catabolic pathway. This high-purity biochemical is essential for research and development in diagnostic and pharmaceutical fields, where precise molecular standards are required. It serves as a critical reference material for laboratories and manufacturers focused on liver function diagnostics, metabolic studies, and the development of calibration standards for clinical analyzers.

Application

• Clinical Diagnostic Reference Standard: Primary use as a calibrator and control material for automated analyzers measuring direct (conjugated) bilirubin in serum.
• Biochemical Research: Investigation of bilirubin metabolism, conjugation processes, and hepatic transport mechanisms.
• Pharmaceutical Development: Used in studies related to jaundice, liver disorders, and the development of therapeutic agents targeting bilirubin-related pathways.
• Enzyme Activity Assays: Substrate for studying the activity of enzymes like UDP-glucuronosyltransferase (UGT1A1).
• Quality Control in IVD Manufacturing: Essential component in the production and quality assurance of in-vitro diagnostic (IVD) kits and reagents.
• Metabolite Standard for HPLC/LC-MS: High-purity standard for analytical method development and validation in chromatographic applications.

Basic Information

Product Name	Bilirubin Glucuronate
CAS No.	27071-67-6
Molecular Formula	C₄₅H₅₂N₄O₂₀
Molecular Weight	936.91 g/mol
Synonyms	Bilirubin Monoglucuronide; Bilirubin Glucuronoside; Direct Bilirubin; Conjugated Bilirubin; BMG; Bilirubin IXα Glucuronide; 1-O-(1-β-D-Glucopyranuronosyl)-bilirubin; 2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid β-D-glucopyranosiduronic acid ester
EINECS	Contact for details

Quality Control

Our Bilirubin Glucuronate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive diagnostic and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our customers' compliance needs in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Due to its hygroscopic and light-sensitive nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake, and handling should be performed under subdued light.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, alkaline aqueous solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.