Description

Harmol Sulfate is a high-purity, sulfate salt derivative of the β-carboline alkaloid harmol. This compound serves as a critical reference standard and analytical reagent in pharmaceutical research and development. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors for method validation, impurity profiling, and pharmacological studies.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of active pharmaceutical ingredients (APIs) and related substances in compliance with pharmacopeial methods.
• Biochemical Research: Employed as a tool compound in studies investigating enzyme inhibition, receptor binding assays, and neurological pathways due to its interaction with various biological targets.
• Analytical Chemistry: Serves as a critical calibration standard in chromatographic techniques like HPLC and LC-MS for quantitative analysis in complex matrices.
• Impurity Profiling: Essential for the characterization and quantification of process-related impurities and degradation products in drug substance and drug product manufacturing.
• Metabolite Studies: Used in pharmacokinetic and metabolic research to study the fate of related compounds in biological systems.

Basic Information

Product Name	Harmol Sulfate
CAS No.	27067-62-5
Molecular Formula	C12H12N2O • H2SO4
Molecular Weight	312.31 g/mol
Synonyms	1-Methyl-9H-pyrido[3,4-b]indol-7-ol sulfate; 7-Hydroxy-1-methyl-9H-pyrido[3,4-b]indole sulfate; Harmol sulphate; 4,9-Dihydro-7-hydroxy-1-methyl-3H-pyrido[3,4-b]indole sulfate
EINECS	Contact for details

Quality Control

Our Harmol Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and spectroscopy. We provide Certificates of Analysis (COA) with detailed results for traceability and regulatory compliance, supporting its use as a pharmaceutical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.