Description

[1R,(-)]-1,2,3,4-Tetrahydro-1-[(4-Hydroxy-3-Methoxyphenyl)Methyl]-6-Methoxy-2-Methylisoquinoline-7-Ol is a high-purity, chiral isoquinoline alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical building block for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in the synthesis of complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Asymmetric Synthesis: Employed as a chiral scaffold or ligand in the synthesis of enantiomerically pure compounds for high-value applications.
• Fine Chemical Production: Acts as a building block for the manufacture of complex specialty chemicals, dyes, and advanced materials.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	[1R,(-)]-1,2,3,4-Tetrahydro-1-[(4-Hydroxy-3-Methoxyphenyl)Methyl]-6-Methoxy-2-Methylisoquinoline-7-Ol
CAS No.	27003-74-3
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	(-)-Reticuline; (R)-Reticuline; (1R)-1,2,3,4-Tetrahydro-1-[(4-hydroxy-3-methoxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol; L-Reticuline; (R)-Reticuline; 1-[(4-Hydroxy-3-methoxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinol, (1R)-; Reticuline, (-)-; NSC 407303
EINECS	Contact for details

Quality Control

Our [1R,(-)]-1,2,3,4-Tetrahydro-1-[(4-Hydroxy-3-Methoxyphenyl)Methyl]-6-Methoxy-2-Methylisoquinoline-7-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.