Description

D-Erythro-Sphingosine-1-Phosphate is a critical bioactive lipid mediator, also known as S1P, that plays a fundamental role in cellular signaling pathways. This high-purity compound is essential for research and development in advanced life sciences due to its regulatory functions in cell proliferation, migration, and immune response. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on immunology, oncology, and cardiovascular disease.

Application

• Biomedical Research: As a key ligand for S1P receptors (S1PR1-5) to study intracellular signaling cascades, cell survival, and angiogenesis.
• Drug Discovery & Development: A vital reference standard and pharmacological tool for screening and developing novel therapeutics targeting the S1P pathway, such as immunomodulators.
• Cell Biology Studies: Used to investigate its role in lymphocyte egress from lymphoid organs, endothelial barrier function, and neural cell regulation.
• Biochemical Assay Development: Serves as a critical component in developing and validating enzyme-linked immunosorbent assays (ELISAs) and other analytical methods for sphingolipid quantification.
• Academic & Pharmaceutical R&D: Fundamental research into inflammatory diseases, multiple sclerosis, cancer metastasis, and tissue regeneration mechanisms.

Basic Information

Product Name	D-Erythro-Sphingosine-1-Phosphate
CAS No.	26993-30-6
Molecular Formula	C18H38NO5P
Molecular Weight	379.48 g/mol
Synonyms	Sphingosine 1-Phosphate; S1P; D-erythro-Sphingosine-1-phosphate; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-Phosphate; Sphing-4-enine-1-phosphate; SPHINGOSINE-1-P; Sphingosine 1-phosphate (d18:1); (2S,3R,4E)-2-Azaniumyl-4-octadecene-1,3-diol 1-dihydrogen phosphate; Erythro-sphingosine-1-phosphate
EINECS	Contact for details

Quality Control

Our D-Erythro-Sphingosine-1-Phosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals to support your critical work in drug discovery and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or film
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.