Description

4,5-Secoakuammilan-17-Oic Acid, 2,5-Epoxy-1,2-Dihydro-16-(Hydroxymethyl)-, Methyl Ester, (2Alpha,16S)- is a specialized, high-purity alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for developing novel bioactive molecules, particularly in the fields of neuroscience and medicinal chemistry. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloids and potential drug candidates targeting neurological pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and compound identification via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and modify the core secoakuammilane skeleton for new biological activities.
• Natural Product Synthesis: Serves as a sophisticated intermediate for the total or semi-synthesis of akuammiline-related alkaloids and their derivatives.
• Biochemical Research: Utilized as a tool compound in pharmacological assays to investigate interactions with specific biological receptors or enzymes.

Basic Information

Product Name	4,5-Secoakuammilan-17-Oic Acid, 2,5-Epoxy-1,2-Dihydro-16-(Hydroxymethyl)-, Methyl Ester, (2Alpha,16S)-
CAS No.	26988-11-4
Molecular Formula	C21H26N2O5
Molecular Weight	386.45 g/mol
Synonyms	(2α,16S)-2,5-Epoxy-1,2-dihydro-16-(hydroxymethyl)-4,5-secoakuammilan-17-oic acid methyl ester; Methyl (2α,16S)-2,5-epoxy-1,2-dihydro-16-(hydroxymethyl)-4,5-secoakuammilan-17-oate; 16(S)-Hydroxymethyl-2,5-epoxy-1,2-dihydro-4,5-secoakuammilan-17-oic acid methyl ester; Secoakuammilane derivative; Akuammiline alkaloid intermediate
EINECS	Contact for details

Quality Control

Our 4,5-Secoakuammilan-17-Oic Acid, 2,5-Epoxy-1,2-Dihydro-16-(Hydroxymethyl)-, Methyl Ester, (2Alpha,16S)- is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at controlled room temperature (15-25°C) or under refrigerated conditions (2-8°C) as specified for the specific batch. The container should be kept in a dry, well-ventilated area. Handle and store under an inert atmosphere if specified for optimal preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.