Description

Starburst(R) (Pamam) Dendrimer, Generation 4.5 is a precisely engineered, hyperbranched polymer with a well-defined, globular architecture and a carboxylic acid-terminated surface. This unique structure provides a high density of functional groups, making it an essential nanoscale building block and delivery platform for advanced research and development. It is particularly valuable for scientists and engineers in the fields of nanotechnology, drug delivery, and materials science who require a monodisperse, functionalizable scaffold.

Application

• Drug Delivery & Nanomedicine: Acts as a versatile carrier or conjugate for targeted delivery of therapeutic agents, genes, and imaging contrast agents due to its controllable size and surface functionality.
• Catalyst Support: Serves as a nanoreactor or support for catalytic metal nanoparticles, enhancing catalytic activity and selectivity in organic synthesis.
• Surface Modification & Coatings: Used to modify material surfaces to improve biocompatibility, create functional thin films, or develop anti-fouling coatings.
• Sensor Development: Employed in the fabrication of chemical and biological sensors, where its surface groups can be tailored for specific analyte binding.
• Advanced Materials Synthesis: Functions as a cross-linker or core component in the synthesis of hybrid organic-inorganic materials, dendrimer-based networks, and nanocomposites.
• Diagnostic Applications: Utilized as a platform for attaching multiple diagnostic labels (e.g., fluorescent dyes, radionuclides) for enhanced imaging and detection.

Basic Information

Product Name	Starburst(R) (Pamam) Dendrimer, Generation 4.5
CAS No.	26937-01-9
Molecular Formula	C622H1252N252O124
Molecular Weight	~14,215 g/mol (theoretical)
Synonyms	PAMAM Dendrimer, Generation 4.5, Carboxylate Terminated; Poly(amidoamine) Dendrimer, G4.5; Starburst Dendrimer; PAMAM G4.5-COOH; Dendrimer, PAMAM, Generation 4.5, COOH-terminated; Nanoscale Polymer; Hyperbranched Polymer G4.5; EDA Core PAMAM Dendrimer G=4.5
EINECS	Contact for details

Quality Control

Our Starburst(R) (Pamam) Dendrimer, Generation 4.5 is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including techniques such as NMR, HPLC, and GPC, to ensure monodispersity, structural integrity, and consistent functional group density. Certificates of Analysis (COA) detailing purity, molecular weight, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and moisture absorption. For long-term stability, consider storage at -20°C. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous solution
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Molecular Weight (GPC)	~14,000 - 15,000 g/mol
Polydispersity Index (PDI)	≤ 1.05
Functional Groups (-COOH)	~128 (theoretical)
Solvent Content (if supplied as solution)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.