Description

(4-Methylphenyl)Sulfonyl Acetate is a versatile organic sulfonate ester, a key building block in advanced chemical synthesis. Its primary value lies in its role as a reactive intermediate for introducing the tosyl (p-toluenesulfonyl) group or as a precursor for other functionalized sulfonates. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, especially those requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers and resins with specific sulfonyl properties.
• Organic Synthesis Reagent: Serves as a versatile reagent for protection/deprotection strategies and as an alkylating agent in complex molecule construction.
• Dye and Pigment Manufacturing: Employed in the synthesis of sulfonated dyes and colorants.
• Cross-coupling Reactions: Utilized as a substrate in palladium-catalyzed cross-coupling reactions to create complex biaryl structures.

Basic Information

Product Name	(4-Methylphenyl)Sulfonyl Acetate
CAS No.	26908-82-7
Molecular Formula	C9H10O4S
Molecular Weight	214.24 g/mol
Synonyms	p-Toluenesulfonyl acetate; Tosyl acetate; 4-Methylbenzenesulfonyl acetate; Acetic acid 4-methylphenyl ester; Acetic acid tosyl ester; p-Tolylsulfonyl acetate; (p-Tolylsulfonyl) acetate; 4-Toluenesulfonic acid acetate ester
EINECS	Contact for details

Quality Control

Our (4-Methylphenyl)Sulfonyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.