Description

Popc CAS NO 26853-31-6 is a high-purity synthetic phospholipid, specifically 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. This compound is a critical building block for creating biomimetic lipid bilayers and vesicles, enabling advanced research and development in life sciences. It is essential for pharmaceutical, biotechnology, and academic laboratories focused on drug delivery systems, membrane biophysics, and model membrane studies.

Application

• Liposome and Nanoparticle Formulation: A primary component for creating stable, uniform liposomes used in targeted drug delivery and vaccine development.
• Membrane Protein Research: Used to reconstitute and stabilize integral membrane proteins in a native-like lipid environment for structural and functional studies.
• Model Membrane Systems: Key lipid for forming supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) to study cell membrane mechanics and signaling.
• Biophysical Analysis: Employed in calorimetry, spectroscopy, and microscopy to investigate lipid-lipid and lipid-protein interactions.
• Diagnostic Assay Development: Serves as a coating or carrier material in diagnostic kits and biosensors to enhance specificity and sensitivity.
• Cosmetic and Dermal Applications: Incorporated into advanced cosmetic formulations for its emollient and skin-barrier repair properties.

Basic Information

Product Name	Popc
CAS No.	26853-31-6
Molecular Formula	C42H82NO8P
Molecular Weight	760.08 g/mol
Synonyms	1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPC; (16:0-18:1) PC; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine (16:0/18:1(9Z)); Avanti Number 850457; LMGP01010906
EINECS	Contact for details

Quality Control

Our Popc is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid profile analysis, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 99.0% (Total Phospholipid Content)
Purity (HPLC - Main Peak)	≥ 98.0%
Lyso-PC Impurity	≤ 0.5%
Solvent Residue	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 mEq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.