Description

Polyvinylsulfuric Acid Potassium Salt is a synthetic polyelectrolyte derivative of polyvinyl alcohol, widely utilized as a model compound for heparin in biochemical and pharmaceutical research. Its consistent polymeric structure and defined sulfation pattern make it an essential reagent for calibrating assays and studying the biological activity of glycosaminoglycans. This product is critical for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic industries who require a reliable and well-characterized heparinoid standard.

Application

• Heparin Calibration Standard: Used as a primary reference standard in quantitative assays (e.g., anti-Factor Xa, anti-Factor IIa) to measure heparin and low-molecular-weight heparin activity.
• Biochemical Research: Serves as a model polyanion in studies of protein-polyanion interactions, enzyme inhibition, and cell surface receptor binding.
• Diagnostic Reagent Manufacturing: A key component in the production of control materials and calibrators for clinical coagulation testing systems.
• Pharmaceutical Development: Employed in pre-clinical research for screening and characterizing novel anticoagulant and antithrombotic agents.
• Quality Control: Acts as a process control standard in the purification and analysis of natural heparin and related sulfated polysaccharides.

Basic Information

Product Name	Polyvinylsulfuric Acid Potassium Salt
CAS No.	26837-42-3
Molecular Formula	(C2H3KO3S)n
Molecular Weight	Variable (Polymer)
Synonyms	PVSK; Potassium Polyvinyl Sulfate; Polyvinyl Sulfate Potassium Salt; Heparinoid Potassium Salt; Poly(Vinyl Sulfate) Potassium Salt; PVS-K; Potassium Salt of Polyvinylsulfuric Acid; Polyvinyl Sulfuric Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Polyvinylsulfuric Acid Potassium Salt is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized for key parameters including sulfation degree, molecular weight distribution, and biological activity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and performance data is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (as Potassium Salt)	≥ 95.0 %
Sulfur Content	16.0 - 18.0 %
pH (1% Solution)	6.0 - 8.0
Loss on Drying	≤ 5.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Biological Activity (Anti-Factor Xa)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.