Description

Hydroxysenkirkine is a pyrrolizidine alkaloid of significant interest in pharmaceutical and biochemical research. This compound matters as a key reference standard and intermediate for the study of hepatotoxic mechanisms and the development of analytical methods for toxin detection. It is primarily needed by research institutions, pharmaceutical R&D departments, and analytical laboratories focused on natural product chemistry, toxicology, and quality control of herbal products.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quantification and identification of pyrrolizidine alkaloids in drug substances and herbal materials.
• Toxicological Research: Serves as a critical reagent in studies investigating the metabolism, bioactivation, and hepatotoxic effects of pyrrolizidine alkaloids.
• Analytical Method Development: Employed in the validation of HPLC, LC-MS, and GC-MS methods for the detection of alkaloid contaminants in food, supplements, and traditional medicines.
• Biochemical Pathway Studies: Utilized to explore biosynthetic pathways in plants and the enzymatic processes involved in alkaloid production.
• Quality Control & Safety Testing: Acts as a marker compound for ensuring the safety and compliance of botanical extracts and herbal preparations by monitoring for toxic alkaloids.

Basic Information

Product Name	Hydroxysenkirkine
CAS No.	26782-43-4
Molecular Formula	C18H25NO6
Molecular Weight	351.40 g/mol
Synonyms	Senkirkine, 13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione; 12-Hydroxysenkirkine; (13Z)-Senkirkine; Otosenine; 12β-Hydroxysenkirkine; Pyrrolizidine alkaloid PA
EINECS	Contact for details

Quality Control

Our Hydroxysenkirkine is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research and analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standard materials to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container sealed to protect the integrity of the material.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.