Description

(12As)-5,6,12,12A-Tetrahydro-2-Hydroxy-3,9,10-Trimethoxy-7-Methylindolo[2,1-A]Isoquinolin-7-Ium is a complex, high-purity alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or reference standard for the study of novel bioactive molecules, particularly those targeting neurological pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds and the development of new therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of novel drug candidates, especially within the alkaloid and isoquinoline chemical families.
• Reference Standard for Analytical Chemistry: Used as a high-purity standard for method development, validation, and quality control in HPLC, LC-MS, and other analytical techniques.
• Biochemical Research: Employed in studies investigating the interaction of complex alkaloid structures with biological targets, such as enzymes or receptors.
• Fine Chemical Synthesis: Acts as a specialized precursor for the custom synthesis of more complex, structurally related molecules for various research applications.
• Academic Research: Utilized in university and institutional labs for chemical education and exploratory research into natural product synthesis and medicinal chemistry.

Basic Information

Product Name	(12As)-5,6,12,12A-Tetrahydro-2-Hydroxy-3,9,10-Trimethoxy-7-Methylindolo[2,1-A]Isoquinolin-7-Ium
CAS No.	26754-21-2
Molecular Formula	C21H24NO4+
Molecular Weight	354.42 g/mol
Synonyms	7-Methylcorynoxan-17-ol, 16-methoxy-, (7α,16α,17α)-; (7α,16α,17α)-7-Methylcorynoxan-17-ol, 16-methoxy-; Corynoxan-17-ol, 7-methyl-16-methoxy-, (7α,16α,17α)-; 16-Methoxy-7-methylcorynoxan-17-ol; Tetrahydroalstonine; Alstonine derivative; Isoquinolinium, 5,6,12,12a-tetrahydro-2-hydroxy-3,9,10-trimethoxy-7-methylindolo[2,1-a]-, (12aS)-
EINECS	Contact for details

Quality Control

Our (12As)-5,6,12,12A-Tetrahydro-2-Hydroxy-3,9,10-Trimethoxy-7-Methylindolo[2,1-A]Isoquinolin-7-Ium is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.