Description

Thiarabine is a synthetic nucleoside analog of significant interest in advanced pharmaceutical research and development. Its unique chemical structure makes it a valuable intermediate for creating novel therapeutic agents, particularly in the fields of oncology and antiviral drug discovery. This compound is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and probe in studies investigating nucleoside metabolism, enzyme inhibition, and mechanism of action.
• Antiviral Agent Development: Explored for its potential activity against a range of viral pathogens due to its structural similarity to natural nucleosides.
• Oncology Research: Investigated for its incorporation into DNA/RNA and its potential to inhibit tumor cell proliferation.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for producing specialized, high-value chemical entities.

Basic Information

Product Name	Thiarabine
CAS No.	26599-17-7
Molecular Formula	C9H11N3O4S
Molecular Weight	257.27 g/mol
Synonyms	9-β-D-Arabinofuranosyl-6-thioguanine; 6-Thioguanine arabinoside; 6-TGara; β-Thioguanosine arabinoside; NSC-712614; Ara-6-TG; 2-Amino-6-mercapto-9-β-D-arabinofuranosyl-9H-purine
EINECS	Contact for details

Quality Control

Our Thiarabine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.