Description

Uridine Diphosphate n-Acetylmannosamine is a critical nucleotide sugar donor essential for the biosynthesis of sialic acid and complex glycoconjugates. This high-purity biochemical is vital for research and development in glycobiology, enzymology, and the synthesis of novel carbohydrate-based therapeutics. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on glycosylation pathways, glycoengineering, and drug discovery.

Application

• Glycobiology Research: A key substrate for studying sialyltransferases and the biosynthesis of sialylated glycoproteins and glycolipids.
• Enzymatic Synthesis: Used as a sugar donor in the enzymatic synthesis of complex oligosaccharides, sialosides, and glycoconjugates.
• Drug Discovery & Development: Essential for screening and developing inhibitors of glycosyltransferases involved in cancer, inflammation, and infectious diseases.
• Biocatalyst Development: Serves as a co-substrate for engineering and characterizing glycosyltransferase enzymes for industrial biocatalysis.
• Diagnostic Reagent Manufacturing: Used in the production of reagents for diagnostic assays targeting sialic acid-related biomarkers.
• Cell Surface Engineering: Applied in metabolic oligosaccharide engineering (MOE) to label and manipulate cell surface glycans for therapeutic and imaging purposes.

Basic Information

Product Name	Uridine Diphosphate n-Acetylmannosamine
CAS No.	26575-17-7
Molecular Formula	C17H27N3O17P2
Molecular Weight	607.35 g/mol
Synonyms	UDP-N-acetylmannosamine; UDP-ManNAc; Uridine 5'-(trihydrogen diphosphate), P'→5'-ester with 2-acetamido-2-deoxy-D-mannose; UDP-Acetylmannosamine; Uridine diphosphate N-acetyl-D-mannosamine; 2-(Acetylamino)-2-deoxy-D-mannose UDP; Uridine 5'-diphospho-N-acetylmannosamine
EINECS	Contact for details

Quality Control

Our Uridine Diphosphate n-Acetylmannosamine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for biochemicals, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Conforms (Enzymatic Assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.