Description

Denudatine is a diterpenoid alkaloid of significant interest in pharmaceutical and biochemical research due to its complex molecular structure and potential biological activity. This high-purity compound is valued for its role as a critical reference standard and a key intermediate in the synthesis of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development laboratories, and manufacturers of fine chemicals focused on neurological and cardiovascular applications.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control, method validation, and regulatory compliance in drug development and manufacturing.
• Biochemical Research: Used as a key reagent in studies investigating ion channel modulation, neuropharmacology, and structure-activity relationships (SAR) of alkaloids.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a crucial building block in the multi-step synthesis of complex therapeutic agents.
• Natural Product Isolation & Analysis: Employed as a benchmark in the extraction, purification, and analytical characterization (e.g., HPLC, LC-MS) of compounds from plant sources like Aconitum species.
• Academic & Institutional Research: Essential for pharmacological screenings, toxicology studies, and academic investigations into diterpenoid alkaloid chemistry.

Basic Information

Product Name	Denudatine
CAS No.	26166-37-0
Molecular Formula	C22H33NO3
Molecular Weight	359.50 g/mol
Synonyms	Denudatine; (1α,14α,16β)-20-Ethyl-1,16-dimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol; 4-(Methoxymethyl)-20-ethyl-1,16-dimethoxyaconitane-7β,8β,14α-triol; Aconitane-7,8,14-triol, 20-ethyl-1,16-dimethoxy-4-(methoxymethyl)-, (1α,14α,16β)-; Isodelphinine derivative
EINECS	Contact for details

Quality Control

Our Denudatine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance profiling, to meet rigorous research-grade specifications. A Certificate of Analysis (COA) detailing identity, purity, and analytical results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.