Description

16-De(Hydroxymethyl)Voachalotine Oxindole is a specialized oxindole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This high-purity compound serves as a critical intermediate for the development of novel bioactive molecules and complex natural product analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of pharmacologically active compounds targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex indole and oxindole-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for neurological targets.
• Natural Product Synthesis: Serves as a precursor in the semi-synthesis or total synthesis of voacanga and related alkaloids.
• Biochemical Research: Employed as a reference standard or probe in studies investigating alkaloid biosynthesis pathways.
• Process Development: Used in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Academic Research: A valuable compound for university laboratories focusing on organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	16-De(Hydroxymethyl)Voachalotine Oxindole
CAS No.	26126-87-4
Molecular Formula	C20H22N2O2
Molecular Weight	322.40 g/mol
Synonyms	16-De(hydroxymethyl)voacangine oxindole; 16-Des(hydroxymethyl)voachalotine oxindole; Voacangine oxindole derivative; 16-Desmethylvoacangine oxindole; (19E)-16-Des(hydroxymethyl)-19,20-didehydro-17-oxovoacangine; Oxindole alkaloid intermediate; 16-Norhydroxymethylvoachalotine oxindole
EINECS	Contact for details

Quality Control

Our 16-De(Hydroxymethyl)Voachalotine Oxindole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.