Description

Poly(2-Ethyl-2-Oxazoline) (CAS NO 25805-17-8) is a versatile, water-soluble synthetic polymer belonging to the polyoxazoline family, valued for its excellent biocompatibility and tunable properties. Its significance lies in its ability to act as a non-ionic, stealth-like polymer for surface modification, drug delivery, and as a reactive intermediate or stabilizer in various formulations. This product is essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty chemical industries seeking advanced polymeric materials for innovative applications.

Application

• Pharmaceutical Excipient & Drug Delivery: Used as a hydrophilic polymer for surface PEGylation, creating stealth nanoparticles and micelles to improve drug circulation time and targeting.
• Bioconjugation & Protein Stabilization: Serves as a reactive platform for coupling with peptides, proteins, and antibodies due to its terminal functional groups, enhancing solubility and stability.
• Hydrogel Formation: Acts as a key component in the synthesis of biocompatible hydrogels for wound dressings, tissue engineering scaffolds, and controlled release systems.
• Surface Modification & Coatings: Applied to modify material surfaces (e.g., medical devices, sensors) to impart antifouling, hydrophilic, or biocompatible properties.
• Viscosity Modifier & Stabilizer: Functions as a thickener and stabilizer in personal care formulations and as a protective colloid in emulsion and dispersion polymerization.
• Gene Delivery Vector: Investigated as a component in non-viral vectors for gene therapy due to its ability to complex with nucleic acids and facilitate cellular uptake.

Basic Information

Product Name	Poly(2-Ethyl-2-Oxazoline)
CAS No.	25805-17-8
Molecular Formula	(C5H9NO)n
Molecular Weight	Varies by grade (typically 5,000 - 500,000 g/mol). Contact for details.
Synonyms	Poly(2-ethyl-2-oxazoline); PEOx; PEtOx; Poly(N-propionylethylenimine); 2-Ethyl-2-oxazoline homopolymer; Poly(2-ethyl-1,3-oxazoline); Polyoxazoline PEtOx; Poly(ethyloxazoline)
EINECS	Contact for details.

Quality Control

Our Poly(2-Ethyl-2-Oxazoline) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistency in molecular weight, polydispersity, and functional end-group integrity. Certificates of Analysis (COA) detailing key parameters such as assay, residual monomer content, and solution characteristics are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). To prevent moisture uptake and potential degradation, keep the container tightly sealed in a dry environment. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (Polymer Content)	> 95%
Molecular Weight (Mn)	As per grade (GPC)
Polydispersity Index (PDI)	< 2.0 (Typical)
Residual Monomer	< 0.5% (HPLC)
Loss on Drying	< 5.0%
pH (in solution)	5.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.