Description

3,7-Diketo, 12-Hydroxy Methyl Ester Of Cholic Acid is a key intermediate in the synthesis of bioactive bile acid derivatives and steroid-based pharmaceuticals. This compound is valued for its defined chemical structure, which serves as a crucial building block for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the study of metabolic pathways and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to bile acid metabolism and steroid hormone pathways.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for the preparation of complex steroid analogs and labeled compounds.
• Academic Research: Employed in universities and research institutes for investigating structure-activity relationships (SAR) and biological mechanisms.
• Process Development: Utilized in scaling up synthetic routes for advanced pharmaceutical ingredients (APIs) in pilot and commercial manufacturing.

Basic Information

Product Name	3,7-Diketo, 12-Hydroxy Methyl Ester Of Cholic Acid
CAS No.	25480-14-2
Molecular Formula	C25H38O6
Molecular Weight	434.57 g/mol
Synonyms	Methyl 3,7,12-trihydroxy-12-oxocholan-24-oate; Methyl 3,7-dioxo-12α-hydroxy-5β-cholan-24-oate; 12α-Hydroxy-3,7-dioxo-5β-cholan-24-oic acid methyl ester; Cholic acid methyl ester derivative; 3,7-Dioxo-12α-hydroxy-5β-cholan-24-oic acid methyl ester; 12-Hydroxy-3,7-diketo methyl cholate
EINECS	Contact for details

Quality Control

Our 3,7-Diketo, 12-Hydroxy Methyl Ester Of Cholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.