Description

Demethyleneberberine is a high-purity, naturally derived alkaloid compound, specifically a key intermediate metabolite of berberine. This compound matters for its significant role in pharmaceutical research and development, offering a crucial building block for studying metabolic pathways and therapeutic mechanisms. It is primarily needed by research institutions, pharmaceutical manufacturers, and nutraceutical companies focused on metabolic health, anti-inflammatory agents, and natural product chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis and research of berberine-based therapeutic agents.
• Biochemical Research: Used as a reference standard and active compound in metabolic pathway and pharmacokinetic studies.
• Natural Product Development: Serves as a key ingredient in the development of high-value nutraceuticals and dietary supplements targeting metabolic syndrome.
• Anti-inflammatory Studies: Investigated for its potential efficacy in cellular models related to inflammation and oxidative stress.
• Academic Research: Employed in universities and R&D labs for pharmacological and phytochemical analysis.

Basic Information

Product Name	Demethyleneberberine
CAS No.	25459-91-0
Molecular Formula	C19H18NO4
Molecular Weight	324.35 g/mol
Synonyms	Demethyleneberberine; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium; Columbamine; Demethylenated Berberine; Berberine, demethylene-; 8-Oxyberberine; 8-Oxoberberine; 25459-91-0
EINECS	Contact for details

Quality Control

Our Demethyleneberberine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Our commitment to quality assurance guarantees material integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.