Description

15,16,17,18,19,20-Hexadehydroyohimban-16-Carboxylic Acid Methyl Ester is a complex, polycyclic indole alkaloid derivative that serves as a critical synthetic intermediate and research chemical. This compound is valued for its intricate molecular architecture, which makes it a valuable building block in advanced organic synthesis and medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers focused on developing novel therapeutic agents or studying alkaloid biosynthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex yohimbine analogs and other indole-based alkaloids with potential pharmacological activity.
• Medicinal Chemistry Research: Used as a core scaffold or a starting material for structure-activity relationship (SAR) studies targeting neurological and cardiovascular receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories analyzing alkaloid-containing materials.
• Academic & Synthetic Studies: Employed in university and institutional research to explore novel organic reactions, cyclization strategies, and the chemistry of polycyclic indole systems.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for investigating biological pathways related to alkaloid function.

Basic Information

Product Name	15,16,17,18,19,20-Hexadehydroyohimban-16-Carboxylic Acid Methyl Ester
CAS No.	25425-11-0
Molecular Formula	C₂₁H₂₂N₂O₂
Molecular Weight	334.42 g/mol
Synonyms	Methyl 15,16,17,18,19,20-hexadehydroyohimban-16-carboxylate; 16-Carbomethoxy-15,16,17,18,19,20-hexadehydroyohimban; Hexadehydroyohimban-16-carboxylic acid methyl ester; Yohimban-16-carboxylic acid, 15,16,17,18,19,20-hexadehydro-, methyl ester; Methyl hexadehydroyohimban-16-carboxylate
EINECS	Contact for details

Quality Control

Our 15,16,17,18,19,20-Hexadehydroyohimban-16-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a Certificate of Analysis (COA) with each shipment, detailing all relevant specifications to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.