Description

(+)-Corlumidine CAS NO 25344-54-1 is a high-purity, naturally occurring isoquinoline alkaloid of significant interest in advanced research and development. This compound serves as a critical reference standard and a valuable building block for synthetic chemistry due to its unique stereochemistry and biological activity profile. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic agents and exploring complex natural product synthesis.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.
• Medicinal Chemistry Research: Serves as a key chiral intermediate or pharmacophore for the synthesis and structure-activity relationship (SAR) study of new bioactive molecules.
• Natural Product Isolation & Analysis: Acts as a benchmark compound in the isolation, identification, and quantification of related alkaloids from plant extracts using techniques like HPLC and LC-MS.
• Biochemical & Pharmacological Studies: Employed in in vitro and in vivo assays to investigate its mechanism of action, receptor binding affinity, and potential therapeutic effects.
• Academic & Institutional Research: Essential for chemical education and advanced research in organic chemistry, phytochemistry, and stereochemistry.

Basic Information

Product Name	(+)-Corlumidine
CAS No.	25344-54-1
Molecular Formula	C₁₆H₁₇NO₅
Molecular Weight	303.31 g/mol
Synonyms	(+)-Corlumidine; Corlumidine; (S)-Corlumidine; 1,2,3,4-Tetrahydro-7-hydroxy-6-methoxy-1-[(4-hydroxyphenyl)methyl]-2-methylisoquinoline-8-carboxylic acid δ-lactone; Fumaricine (related isomer); Isoquinoline alkaloid
EINECS	Contact for details

Quality Control

Our (+)-Corlumidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade or reference standard requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.