Description

(3α,5α,12β,19α,20R)-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative with a rigid cyclized structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold in organic synthesis for developing novel bioactive molecules. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for complex alkaloid-based drug candidates.
• Organic Synthesis Research: Valuable precursor for constructing intricate molecular architectures in academic and industrial research.
• Medicinal Chemistry: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Natural Product Synthesis: Intermediate in the total or semi-synthesis of complex aspidosperma-type indole alkaloids.

Basic Information

Product Name	(3α,5α,12β,19α,20R)-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	25343-00-4
Molecular Formula	C22H28N2O2
Molecular Weight	352.47 g/mol
Synonyms	2α,20-Cycloaspidospermidine-3-carboxylic acid methyl ester; Methyl (3α,5α,12β,19α,20R)-2α,20-cycloaspidospermidine-3-carboxylate; 2α,20-Cyclotabersonine; 2α,20-Cyclovincadifformine; Tabersonine derivative; Aspidospermidine alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (3α,5α,12β,19α,20R)-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation, to ensure identity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.