Description

4-Aminophenyl 2,3,4-Tri-o-Acetyl-β-D-Glucuronide Methyl Ester is a key protected glucuronide derivative, serving as a critical synthetic intermediate and analytical standard. This compound is essential for researchers and manufacturers requiring a stable, acetyl-protected precursor for the synthesis of glucuronide metabolites and conjugates. It is primarily utilized in pharmaceutical research, analytical chemistry, and the development of diagnostic reagents.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of drug metabolites, particularly glucuronide conjugates for pharmacokinetic and metabolic studies.
• Analytical Reference Standard: Used for method development, calibration, and quantification in High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) analyses.
• Biochemical Research: Employed in enzymatic studies involving glucuronosyltransferases (UGTs) to investigate conjugation pathways.
• Diagnostic Reagent Development: Acts as a starting material for synthesizing labeled compounds or probes used in clinical diagnostics and immunoassays.
• Organic Synthesis Building Block: The protected functional groups allow for selective deprotection and further chemical modifications in complex molecule synthesis.

Basic Information

Product Name	4-Aminophenyl 2,3,4-Tri-o-Acetyl-β-D-Glucuronide Methyl Ester
CAS No.	25218-22-8
Molecular Formula	C19H23NO10
Molecular Weight	425.39 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-β-D-glucopyranosyluronate) 4-aminophenyl ester; p-Aminophenyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronic acid methyl ester; 4-Aminophenyl β-D-glucopyranosiduronic acid, 2,3,4-triacetate, methyl ester; 4-Aminophenyl triacetyl-β-D-glucuronide methyl ester; p-Aminophenyl tri-O-acetyl-β-D-glucuronide methyl ester; AGME; Protected p-aminophenyl glucuronide.
EINECS	Contact for details

Quality Control

Our 4-Aminophenyl 2,3,4-Tri-o-Acetyl-β-D-Glucuronide Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.