Description

Uridine Diphosphate Glucose, [Glucose-14C(U)] is a radiolabeled nucleotide sugar derivative where the glucose moiety is uniformly labeled with carbon-14. This compound is a critical biochemical tool for tracing and quantifying metabolic pathways involving glucose incorporation, such as glycogen synthesis and glycosylation reactions. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors who require precise, high-specific-activity tracers for metabolic studies and enzymatic assay development.

Application

• Enzymology & Metabolic Pathway Research: Used as a radiolabeled substrate to study the kinetics and mechanisms of enzymes like glycogen synthase and glucosyltransferases.
• Glycobiology Studies: Essential for tracing the incorporation of glucose into glycoproteins, proteoglycans, and other glycosylated molecules.
• Pharmaceutical R&D: Employed in drug discovery to investigate compounds that modulate carbohydrate metabolism and glycosylation processes.
• Diagnostic Assay Development: Serves as a key component in the development of radiometric assays for clinical diagnostics and biochemical testing.
• Biotechnology Production: Used in quality control and process development for biologics where glycosylation patterns are critical.
• Academic Research: A fundamental reagent for university and institutional research into carbohydrate metabolism and cell biology.

Basic Information

Product Name	Uridine Diphosphate Glucose, [Glucose-14C(U)]
CAS No.	25193-88-8
Molecular Formula	C15H22N2O17P2 * (14C-labeled)
Molecular Weight	566.30 g/mol (unlabeled)
Synonyms	UDP-Glucose, [Glucose-14C(U)]; UDP-[14C]Glucose; UDP-α-D-[U-14C]Glucose; Uridine 5'-(α-D-Glucopyranosyl Diphosphate), [Glucose-14C(U)]; Uridine Diphosphoglucose-14C; UDPG-14C; 1-[(2R,3R,4S,5R)-5-[2-[[[(2R,3S,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxolan-3-one (14C-labeled)
EINECS	Contact for details

Quality Control

Every batch of Uridine Diphosphate Glucose, [Glucose-14C(U)] is manufactured and tested to meet the stringent requirements for radiochemical purity and specific activity in research applications. Our quality assurance includes rigorous analytical controls such as HPLC and TLC to verify identity, purity, and radiochemical concentration. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, and solvent composition is provided with each shipment to ensure traceability and compliance with your experimental protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container sealed under an inert atmosphere. Follow all applicable laboratory safety and radiation safety guidelines for handling and disposal.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (HPLC, TLC)	Conforms to reference standard
Specific Activity	Customizable (e.g., 200-600 mCi/mmol). Contact for details.
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 90%
Solvent	Ethanol:Water solution or as specified
Concentration	Customizable (e.g., 0.1 mCi/mL). Contact for details.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.