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Undecaprenyl Phosphate CAS NO 25126-51-6


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CAS No.:25126-51-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Undecaprenyl Phosphate is a critical phosphorylated lipid carrier molecule, also known as bactoprenol phosphate, essential in bacterial cell wall biosynthesis. Its primary value lies in its role as a membrane-anchored transporter for the peptidoglycan and teichoic acid precursors across the cytoplasmic membrane in prokaryotes. This makes it a vital biochemical tool for researchers in microbiology, enzymology, and pharmaceutical development, particularly those investigating novel antibacterial targets and pathways.

Application

  • Biochemical Research: Essential substrate for in vitro studies of bacterial cell wall synthesis enzymes, including MurG and other glycosyltransferases.
  • Antibiotic Mechanism Studies: Used to investigate the mode of action and resistance mechanisms of antibiotics like bacitracin, which targets the dephosphorylation of undecaprenyl pyrophosphate.
  • Enzyme Assay Development: Serves as a key component in high-throughput screening assays for discovering new inhibitors of bacterial cell wall assembly.
  • Metabolic Pathway Analysis: A crucial intermediate for studying the cytoplasmic steps of peptidoglycan and polysaccharide biosynthesis pathways.
  • Membrane Biophysics: Used in model membrane systems to study the interaction and flipping of lipid-linked oligosaccharides.

Basic Information

Product Name Undecaprenyl Phosphate
CAS No. 25126-51-6
Molecular Formula C55H91O4P
Molecular Weight 839.28 g/mol
Synonyms Bactoprenyl Phosphate; Undecaprenol Phosphate; C55-Prenyl Phosphate; (all-E)-3,7,11,15,19,23,27,31,35,39,43-Undecamethyltetratetracontapentaen-1-yl Dihydrogen Phosphate; Polyprenyl Phosphate (C55); Dolichyl Phosphate (bacterial analogue); Glycosyl Carrier Lipid Phosphate
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Quality Control

Our Undecaprenyl Phosphate is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability parameters. We adhere to rigorous analytical standards, utilizing techniques such as HPLC, NMR, and MS for characterization, ensuring the material meets the exacting requirements of biochemical and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is light-sensitive and should be handled under subdued light. Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or film
Identification (HPLC/MS) Conforms to reference standard
Assay (HPLC) ≥ 95%
Solubility Soluble in chloroform, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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