Description

2-Deoxy-L-Glucose is a synthetic glucose analog where the 2-hydroxyl group is replaced by hydrogen, making it a valuable biochemical tool for metabolic research. This compound is crucial for studying glucose metabolism, hexokinase inhibition, and cellular energy pathways due to its competitive inhibitory properties. It serves as an essential research chemical for pharmaceutical development, academic institutions, and biotechnology companies focused on oncology, neurology, and metabolic disorders.

Application

• Biochemical Research: Used as a potent inhibitor of glycolysis and glucose metabolism in cell culture and in vitro studies.
• Pharmaceutical Development: Investigated in preclinical research for potential applications in cancer therapy and antiviral agents.
• Metabolic Pathway Analysis: A key tool for studying the hexose monophosphate shunt and energy homeostasis in various biological systems.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in biochemistry and cell biology.
• Diagnostic Agent Research: Explored for use in positron emission tomography (PET) imaging and other diagnostic techniques.
• Reference Standard: Serves as a high-purity analytical standard for quality control in related pharmaceutical and research compound manufacturing.

Basic Information

Product Name	2-Deoxy-L-Glucose
CAS No.	25029-33-8
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	2-Deoxy-L-arabino-hexose; L-2-Deoxyglucose; 2-Deoxy-L-glucose; 2-DG-L; (2R,3S,4R,5S)-2-(Hydroxymethyl)tetrahydrofuran-3,4,5-triol; 2-Deoxy-L-mannose; L-(-)-2-Deoxyglucose; 2-Deoxy-L-arabino-Hexopyranose
EINECS	246-574-0

Quality Control

Our 2-Deoxy-L-Glucose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	-45° to -50° (c=1 in H2O)
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.