Description

n-Acetylneuraminic Acid, 2,3-Dehydro-2-Deoxy-, Sodium Salt is a chemically modified derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound serves as a potent and specific inhibitor of neuraminidase (sialidase) enzymes, making it an essential tool for research into viral infection mechanisms, cellular recognition, and glycan processing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for enzyme inhibition studies, antiviral research, and the development of glycoconjugate-based therapeutics.

Application

• Neuraminidase Inhibition Studies: A key research tool for investigating the function and mechanism of viral and bacterial neuraminidases.
• Antiviral Research: Used in the study of influenza virus and other pathogens that utilize sialic acid for host cell entry and release.
• Glycobiology Research: Essential for probing sialic acid metabolism, glycan biosynthesis, and cell surface receptor interactions.
• Diagnostic Reagent Development: Serves as a reference standard or key component in assays designed to detect neuraminidase activity or screen for inhibitors.
• Biochemical Pathway Analysis: Used to elucidate pathways involving sialic acid cleavage and its role in cellular signaling and immune response.
• Pharmaceutical Intermediates: Potential starting material or intermediate in the synthesis of more complex glycomimetic drugs.

Basic Information

Product Name	n-Acetylneuraminic Acid, 2,3-Dehydro-2-Deoxy-, Sodium Salt
CAS No.	24967-27-9
Molecular Formula	C11H16NNaO8
Molecular Weight	313.24 g/mol
Synonyms	2-Deoxy-2,3-didehydro-N-acetylneuraminic Acid Sodium Salt; DANA Sodium Salt; Neu5Ac2en Sodium Salt; 2,3-Didehydro-2-deoxy-N-acetylneuraminic Acid Sodium Salt; Zanamivir Intermediate; Neuraminidase Inhibitor; 5-Acetamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our n-Acetylneuraminic Acid, 2,3-Dehydro-2-Deoxy-, Sodium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.