Description

(13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-9α-Ol is a complex, semi-synthetic alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in neuropharmacology and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel analgesic or neuroactive pharmaceutical candidates.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances via HPLC, LC-MS, or GC-MS.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Biochemical Tool Compound: Employed in in vitro and ex vivo studies to investigate specific receptor interactions and signaling pathways.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing production processes for related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-9α-Ol
CAS No.	24695-69-0
Molecular Formula	C₂₀H₂₅NO₄
Molecular Weight	343.42 g/mol
Synonyms	9α-Hydroxy-17-methyl-7,8-didehydro-4,5α-epoxy-3-methoxy-13β,14β-hasubanan; 17-Methyl-9α-hydroxy-7,8-didehydro-4,5α-epoxy-3-methoxy-13β,14β-hasubanan; Hasubanan alkaloid derivative; (-)-9α-Hydroxy-17-methyl-7,8-didehydro-4,5α-epoxy-3-methoxy-13β,14β-hasubanan
EINECS	Contact for details

Quality Control

Our (13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-9α-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, chiral purity determination, and identity confirmation (IR, NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP intermediate requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.