Description

(+)-Muscarine Iodide CAS NO 24570-49-8 is a high-purity, enantiomerically pure salt of the potent muscarinic acetylcholine receptor agonist. This compound is of critical importance for neuroscience and pharmacological research, serving as a key reference standard and tool compound. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers engaged in neurochemical studies, receptor binding assays, and the development of cholinergic system modulators.

Application

• Neuroscience Research: As a selective agonist for muscarinic acetylcholine receptors (mAChRs) in studies of the parasympathetic nervous system.
• Pharmacological Reference Standard: Used for calibrating bioassays, validating analytical methods (HPLC, LC-MS), and quantifying muscarinic activity.
• Receptor Binding & Characterization: Essential for in vitro competitive binding assays to determine receptor affinity (Ki/IC50 values) and subtype specificity.
• Drug Discovery & Development: A tool compound for screening and evaluating potential anticholinergic or cholinergic drugs.
• Toxicology Studies: Employed in research investigating cholinergic toxicity and the effects of muscarinic overstimulation.
• Academic & Clinical Research: Supports fundamental research into cognitive function, smooth muscle contraction, glandular secretion, and heart rate regulation.

Basic Information

Product Name	(+)-Muscarine Iodide
CAS No.	24570-49-8
Molecular Formula	C9H20INO2
Molecular Weight	285.17 g/mol
Synonyms	(+)-Muscarine iodide; L-(+)-Muscarine iodide; Muscarine iodide; (2S,4R,5S)-4-Hydroxy-5-methyl-2-(trimethylammonio)methyl-1,3-dioxolane iodide; (2S,4R,5S)-(4-Hydroxy-5-methyl-2-trimethylammoniomethyl-1,3-dioxolan) iodide; AGN-PC-0E6KJ1; (2S,4R,5S)-2-[(Trimethylammonio)methyl]-5-methyl-1,3-dioxolan-4-ol iodide
EINECS	Contact for details

Quality Control

Our (+)-Muscarine Iodide is manufactured under controlled conditions to ensure high chemical and enantiomeric purity suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.