Description

17-α-Hydroxy-16-β-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound matters for its role as a key precursor in the synthesis of potent corticosteroid and progestogen derivatives, enabling the creation of advanced therapeutic agents. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on developing next-generation steroid-based medications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced corticosteroid drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing novel anti-inflammatory and immunosuppressive agents.
• Steroid Hormone Research: Serves as a key reference standard and starting material in biochemical and pharmacological studies of steroid action.
• Process Chemistry & Scale-Up: Employed in optimizing manufacturing routes for complex steroid molecules in pilot plants and commercial production.
• Fine Chemical Synthesis: Utilized by custom synthesis and contract manufacturing organizations (CMOs) for producing specialized steroid derivatives.

Basic Information

Product Name	17-α-Hydroxy-16-β-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
CAS No.	24510-55-2
Molecular Formula	C₂₄H₃₂O₅
Molecular Weight	400.51 g/mol
Synonyms	16β-Methylprednisolone 21-Acetate; 16β-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-Acetate; 16β-Methylprednisolone Acetate; (11β,16β)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate; 16β-Methyl-δ¹-prednisolone 21-acetate; Medrol Acetate (related); 16-Methylprednisolone Acetate
EINECS	Contact for details

Quality Control

Our 17-α-Hydroxy-16-β-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flame, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.