Description

H-Gly-Arg-βna CAS NO 24387-24-4 is a synthetic peptide derivative, specifically a dipeptide amide, designed for advanced research and development applications. This compound serves as a crucial building block and biochemical tool in the study of enzyme kinetics, receptor binding, and proteolytic pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on peptide chemistry, medicinal chemistry, and biochemical assay development.

Application

• Pharmaceutical Research & Development: As a specialized substrate or intermediate in the synthesis of novel therapeutic peptides and protease inhibitors.
• Biochemical Assays: Used as a model compound or a specific substrate in enzymatic studies, particularly for investigating arginine-specific proteases like trypsin or trypsin-like enzymes.
• Medicinal Chemistry: Acts as a key synthon for structure-activity relationship (SAR) studies to optimize peptide-based drug candidates.
• Proteomics Research: Employed in the development and calibration of analytical methods such as HPLC and mass spectrometry for peptide analysis.
• Academic & Institutional Research: A valuable reagent for fundamental studies in biochemistry, enzymology, and peptide science within university laboratories.

Basic Information

Product Name	H-Gly-Arg-βna
CAS No.	24387-24-4
Molecular Formula	C₁₄H₂₁N₅O₃
Molecular Weight	307.35 g/mol
Synonyms	Glycyl-L-arginine 4-nitroanilide acetate salt; H-Gly-Arg-pNA; Gly-Arg-pNA; Gly-Arg-4-NA; L-Glycyl-L-arginine 4-nitroanilide; G-R-pNA; Substrate for trypsin; Boc-Gly-Arg-4-nitroanilide (related protected form)
EINECS	Contact for details

Quality Control

Our H-Gly-Arg-βna is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation (IR, NMR). We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay results. Our quality commitment ensures material consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For extended storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.