Description

Lignoceroyl-Coenzyme A is a high-purity, long-chain fatty acyl-CoA ester, a critical biochemical intermediate in lipid metabolism. This compound is essential for researchers and manufacturers studying or manipulating the biosynthesis of very long-chain fatty acids, sphingolipids, and wax esters. It serves as a vital substrate for enzymatic assays and is a key reagent in metabolic pathway research within the pharmaceutical, biotechnology, and life science sectors.

Application

• Enzymology Research: Used as a specific substrate for acyl-CoA synthetases, elongases (ELOVL), and other enzymes involved in fatty acid elongation pathways.
• Lipidomics & Metabolic Studies: A crucial reagent for in vitro studies of sphingolipid biosynthesis, ceramide production, and complex lipid assembly.
• Drug Discovery & Screening: Employed in high-throughput assays to identify and characterize inhibitors or activators of enzymes that utilize lignoceroyl-CoA as a substrate.
• Biochemical Standard: Serves as a certified reference material for the quantification of acyl-CoA species in biological samples via LC-MS or HPLC.
• Cell Biology: Used in studies investigating the role of very long-chain fatty acids in cellular processes, membrane structure, and signaling.
• Cosmeceutical Research: Applied in research focused on skin barrier function and the synthesis of epidermal lipids.

Basic Information

Product Name	Lignoceroyl-Coenzyme A
CAS No.	24305-30-4
Molecular Formula	C45H82N7O17P3S
Molecular Weight	1122.13 g/mol
Synonyms	Lignoceroyl-CoA; Tetracosanoyl-Coenzyme A; Coenzyme A, S-tetracosanoate; (24R)-24-Hydroxy-24-oxotetracosanoic acid; 3'-Phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(tetracosanoylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate); Tetracosanoyl-CoA; C24:0-CoA; Lignoceric acyl-CoA
EINECS	Contact for details

Quality Control

Our Lignoceroyl-Coenzyme A is manufactured under strict quality-controlled conditions suitable for research applications. Each batch is characterized to ensure identity, purity, and stability. Certificates of Analysis (COA) detailing purity (by HPLC), identity confirmation (by MS, NMR), and other critical parameters are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO, ethanol
Biological Activity	Functional in standard enzymatic assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.