Description

Cinchonine Hydrochloride is a high-purity alkaloid salt derived from cinchona bark, valued for its distinct stereochemistry and biological activity. This compound serves as a critical chiral building block and resolving agent in advanced organic synthesis and pharmaceutical development. It is essential for research and production in the pharmaceutical, fine chemical, and analytical reagent industries, where precise stereochemical control is paramount.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in asymmetric synthesis and purification processes.
• Pharmaceutical Intermediate: Acts as a key precursor in the synthesis of specialized active pharmaceutical ingredients (APIs).
• Catalyst Ligand: Employed in the development of chiral catalysts for stereoselective chemical reactions.
• Analytical Standard: Serves as a reference standard in chromatographic analysis (HPLC, TLC) and quality control laboratories.
• Biochemical Research: Utilized in pharmacological studies and as a tool compound in biological assays.
• Fine Chemical Synthesis: Applied in the preparation of complex organic molecules requiring specific stereocenters.

Basic Information

Product Name	Cinchonine Hydrochloride
CAS No.	24302-67-8
Molecular Formula	C19H22N2O • HCl
Molecular Weight	322.85 g/mol
Synonyms	Cinchonine HCl; (8α,9R)-Cinchonan-9-ol Hydrochloride; Cinchonine Monohydrochloride; Cinchonine Hydrochloride Salt; Cinchonan-9-ol, hydrochloride, (8α,9R)-; α-(2-Quinolyl)-5-vinyl-2-quinuclidinemethanol Hydrochloride
EINECS	Contact for details

Quality Control

Our Cinchonine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Rotation	-110° to -115° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.