Description

(3α,14R,16α)-14,15-Dihydro-14α-Hydroxyeburnamenine-14-Methanol is a high-purity, complex indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation medicines. Our supply is characterized by stringent quality control, ensuring reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for Vincamine derivatives and related nootropic or vasodilatory agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in pharmacological studies to investigate mechanisms of action related to cerebral blood flow and cognitive function.
• Process Chemistry: Serves as a starting material or intermediate in scale-up and optimization campaigns for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry and medicinal chemistry projects.
• Custom Synthesis: A precursor for the tailored synthesis of specialized analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(3α,14R,16α)-14,15-Dihydro-14α-Hydroxyeburnamenine-14-Methanol
CAS No.	24184-23-4
Molecular Formula	C20H26N2O2
Molecular Weight	326.43 g/mol
Synonyms	14-Hydroxyeburnamenine-14-methanol; 14α-Hydroxy-14,15-dihydroeburnamenine-14-methanol; (14R)-14,15-Dihydro-14-hydroxyeburnamenine-14-methanol; Eburnamenine-14-methanol, 14,15-dihydro-14-hydroxy-; Apovincaminic acid derivative; Vincamine related compound
EINECS	Contact for details

Quality Control

Every batch of (3α,14R,16α)-14,15-Dihydro-14α-Hydroxyeburnamenine-14-Methanol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.